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商品详情：
英文名称：CFH
中文名称：补体因子H重组兔单克隆抗体
别 名:CFAH_HUMAN; Complement factor H; HF; HF1; HF2; H factor 1; Factor H;
研究领域:肿瘤 免疫学 生长因子和激素
抗体来源:Rabbit
克隆类型:Monoclonal
交叉反应:Human,
产品应用:WB=1:500-2000 IHC-P=1:100-500 ICC=1:50-100 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量:51/137kDa
检测分子量150 kDa
细胞定位:分泌型蛋白
性 状:Liquid
浓 度:1mg/ml
免 疫 原:KLH conjugated synthetic peptide derived from human Factor H
亚 型:IgG
纯化方法:affinity purified by Protein A
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
补体因子H重组兔单克隆抗体产品介绍:This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011]
Function:
Factor H functions as a cofactor in the inactivation of C3b by factor I and also increases the rate of dissociation of the C3bBb complex (C3 convertase) and the (C3b)NBB complex (C5 convertase) in the alternative complement pathway.
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