NCKAP5蛋白抗体

公司产品仅供科研研究实验，不得用于临床！

商品详情：

英文名称：NCKAP5
中文名称：NCKAP5蛋白抗体
别    名:ERIH1; ERIH2; NAP-5; NAP5; Nck-associated protein 5; NCKAP5; NCKP5_HUMAN; Peripheral clock protein.

研究领域:信号转导  跨膜蛋白  细胞膜蛋白

抗体来源:Rabbit

克隆类型:Polyclonal

交叉反应:(predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )

产品应用:ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理论分子量:208kDa

细胞定位:细胞膜

性    状:Liquid

浓    度:1mg/ml

免 疫 原:KLH conjugated synthetic peptide derived from human NCKAP5: 1-100/1909

亚    型:IgG

纯化方法:affinity purified by Protein A

缓 冲 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

注意事项:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
NCKAP5蛋白抗体产品介绍:NAP5 (Nck-associated protein 5), also known as peripheral clock protein, NCKAP5 or ERIH, is a 1,909 amino acid nuclear protein that is expressed in fetal and adult brain, leukocytes and fetal fibroblasts. Containing pro-rich sequences, NAP5 interacts with the adapter protein Nck via the SH3-containing region. Existing as four alternatively spliced isoforms, the gene encoding NAP5 maps to human chromosome 2q21.2 and mouse chromosome 1 E3. Human chromosome 2, the second largest human chromosome, consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene present on chromosome 2. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome, is due to mutations in the ALMS1 gene.

Interacts with the SH3-containing region of the adapter protein NCK.