LHX5蛋白抗体

公司产品仅供科研研究实验，不得用于临床！

商品详情：

英文名称：LHX5
中文名称：LHX5蛋白抗体
别    名:LHX 5; Lhx5; LHX5_HUMAN; LIM homeobox 5; LIM homeobox protein 5; LIM/homeobox protein Lhx5; MGC129689.

研究领域:细胞生物  神经生物学  细胞分化  表观遗传学

抗体来源:Rabbit

克隆类型:Polyclonal

交叉反应:(predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )

产品应用:WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理论分子量:44kDa

细胞定位:细胞核

性    状:Liquid

浓    度:1mg/ml

免 疫 原:KLH conjugated synthetic peptide derived from human LHX5: 25-130/402

亚    型:IgG

纯化方法:affinity purified by Protein A

缓 冲 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

注意事项:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
LHX5蛋白抗体产品介绍:During development, genetically distinct subtypes of motor neurons express unique combinations of LIM-type homeodomain factors, which regulate cell migration and guide motor axons to establish the fidelity of a binary choice in axonal trajectory. The LIM gene family encodes a set of gene products, which carry the LIM domain, a unique cysteine-rich zinc-binding domain. At least 40 members of this family have been identified in vertebrates and invertebrates, and are distributed into 4 groups according to the number of LIM domains and to the presence of homeodomains and kinase domains. The human LHX5 gene maps to chromosome 12q23-q24 and encodes a 402 amino acid protein. The hippocampus contains the neural circuitry, which is crucial for cognitive functions such as learning and memory. LHX5 regulates precursor cell proliferation and neuronal differentiation and migration during hippocampal development.

Plays an essential role in the regulation of neuronal differentiation and migration during development of the central nervous system.