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商品详情:
英文名称:Ki-67
中文名称:Ki67蛋白抗体
别 名:Antigen identified by monoclonal antibody Ki 67; Antigen KI67; KIA; Ki67; MKI67; Proliferation related Ki 67 antigen; Antigen KI-67; KI67_HUMAN.
研究领域:肿瘤 细胞生物 神经生物学 细胞周期蛋白 细胞分化 细胞类型标志物
抗体来源:Mouse
克隆类型:Monoclonal
交叉反应:Human, Mouse, Rat,
产品应用:IHC-P=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量:358kDa
细胞定位:细胞核
性 状:Liquid
浓 度:1mg/ml
免 疫 原:Recombinant human Ki-67
亚 型:IgG
纯化方法:affinity purified by Protein G
缓 冲 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事项:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Ki67蛋白抗体产品介绍:Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.
Thought to be required for maintaining cell proliferation.