G蛋白α亚单位蛋白Q抗体

公司产品仅供科研研究实验，不得用于临床！

商品详情：

英文名称：GNAQ
中文名称：G蛋白α亚单位蛋白Q抗体
别    名:G ALPHA q; G protein alpha Q; GAQ; Guanine nucleotide binding protein alpha q; Guanine nucleotide binding protein G q subunit alpha; GNAQ_HUMAN.

研究领域:肿瘤  心血管  细胞生物  神经生物学  信号转导  G蛋白偶联受体

抗体来源:Rabbit

克隆类型:Polyclonal

交叉反应: Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Cow, Horse, Rabbit, )

产品应用:WB=1:500-2000 ELISA=1:5000-10000

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理论分子量:42kDa

细胞定位:细胞核 细胞膜

性    状:Liquid

浓    度:1mg/ml

免 疫 原:KLH conjugated synthetic peptide derived from human GNAQ: 51-150/359

亚    型:IgG

纯化方法:affinity purified by Protein A

缓 冲 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

注意事项:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
G蛋白α亚单位蛋白Q抗体产品介绍: GNAQ belong to the family of heterotrimeric Guanine nucleotide-binding proteins proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. GNAQ is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta. in recent studies over expression of GNAQ is associated with cardiomyocyte apoptosis.

Function:

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity).