公司产品仅供科研研究实验,不得用于临床!
商品详情:
英文名称:GABBR2
中文名称:G氨基丁酸B型受体2重组兔单克隆抗体
别 名:GABR2_HUMAN; Gamma-aminobutyric acid type B receptor subunit 2; GPR51; GPRC3B; GABA-B receptor 2; GABA B Receptor 2; GABA-B-R2; GABA-BR2; GABABR2; Gb2; G-protein coupled receptor 51; HG20;
研究领域:细胞生物 神经生物学 信号转导 细胞膜受体 G蛋白偶联受体
抗体来源:Rabbit
克隆类型:Monoclonal
交叉反应:(predicted: Human, Mouse, Rat, )
产品应用:WB=1:500-1000 IHC-P=1:100-500 ICC=1:50-100 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量:103kDa
细胞定位:细胞浆 细胞膜
性 状:Liquid
浓 度:1mg/ml
免 疫 原:KLH conjugated synthetic peptide derived from human GABBR2
亚 型:IgG
纯化方法:affinity purified by Protein A
缓 冲 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
G氨基丁酸B型受体2重组兔单克隆抗体产品介绍:The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010]
Subcellular Location:
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Note=Moreover coexpression of GABA-B-R1 and GABA-B-R2 appears to be a prerequisite for maturation and transport of GABA-B-R1 to the plasma membrane.