信号转导衔接蛋白1抗体

公司产品仅供科研研究实验，不得用于临床！

商品详情：

英文名称：STAM
中文名称：信号转导衔接蛋白1抗体
别    名:Signal transducing adapter molecule 1; Signal transducing adapter molecule 2; Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1; Signal transducing adaptor molecule; STAM 1; STAM-2; STAM1; Stam2; STAM2_HUMAN; DKFZp686J2352; Hrs-binding protein; HSE1 homolog; OTTHUMP00000019237.

研究领域:细胞生物  信号转导  细胞周期蛋白  细胞分化

抗体来源:Rabbit

克隆类型:Polyclonal

交叉反应:Rat,  (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, Sheep, )

产品应用:ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理论分子量:59kDa

细胞定位:细胞浆 细胞膜

性    状:Liquid

浓    度:1mg/ml

免 疫 原:KLH conjugated synthetic peptide derived from human STAM: 101-200/540

亚    型:IgG

纯化方法:affinity purified by Protein A

保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
信号转导衔接蛋白1抗体注意事项:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Function:

Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity).