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商品详情：
英文名称：AR/Androgen receptor Rabbit pAb
中文名称：AR/Androgen receptor Rabbit pAb雄激素受体（AR）抗体
研究领域:免疫学 信号转导 细胞凋亡 细胞周期蛋白 转录调节因子
抗体来源:Rabbit
克隆类型:Polyclonal
交叉反应:Human, Mouse, Rat (predicted: Cow )
产品应用:WB (1:500-2000)
理论分子量:43/101 kDa
细胞定位:细胞核 细胞质
性 状:Liquid
浓 度:1mg/ml
免 疫 原: KLH conjugated synthetic peptide derived from human Androgen receptor: 701-800/919.
亚 型:IgG
纯化方法:affinity purified by Protein A
缓 冲 液:0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Androgen Receptor (AR) Polyclonal Antibody, Rabbit产品介绍:The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes.This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
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